Extremely high cpu usage and slow performance after upgrade from 5.5.52 to 10.1.29

After upgrade from MariaDB 5.5.52 to 10.1.19 the performance of our application is about 5 times slower than before.

It is noticeable that the MariaDB 10.1.19 has a cpu usage of 95%.
With MariaDB 5.5.52 the cpu usage was only about 5%.

I appended 2 pictures which shows the difference between these 2 versions.
For both versions we used the same server with the same test application.
The only difference is the upgrade of MariaDB.

The settings of my.ini are appended.