2 nodes running mysql Ver 15.1 Distrib 10.1.31-MariaDB, for Linux (x86_64) using readline 5.1. 

- Hosts: Physical Hosts running CentOS 7.4.1708 (Core), 32 CPUs, 64 GB RAM 

1 node is the master and the other is slave. 

# MariaDB Configuration: 

[mysqld] 
datadir=/mysql/data/mysql 
socket=/mysql/data/mysql/mysql.sock 
open_files_limit = 65535 
max_connections = 500 
user=mysql 
binlog_format=ROW 
default_storage_engine=InnoDB 
innodb_autoinc_lock_mode=2 
innodb_flush_log_at_trx_commit=0 
wsrep_provider=/usr/lib64/galera/libgalera_smm.so 
wsrep_provider_options="gcache.size=50G; gcache.page_size=1024M; gcs.fc_limit=1000000; gcs.fc_master_slave=yes" 
wsrep_cluster_name="zabbixdb_cluster" 
wsrep_cluster_address="gcomm://10.1.1.1,10.1.1.2" 
wsrep_on=ON 
wsrep_node_name=AAAAAA 
wsrep_slave_threads=32 

wsrep_sst_auth=root:xxxxxxx 
wsrep_sst_method=xtrabackup 

innodb_autoextend_increment = 256 
innodb_buffer_pool_instances = 52 
innodb_buffer_pool_size = 52G 
innodb_concurrency_tickets = 5000 
innodb_file_per_table = 1 
innodb_flush_method = O_DIRECT 
innodb_log_file_size = 512M 
innodb_log_files_in_group = 4 
innodb_old_blocks_time = 1000 
innodb_open_files = 2048 
innodb_stats_on_metadata = OFF 
innodb_lock_wait_timeout = 50 
innodb_io_capacity = 2000 

optimizer_switch = 'index_condition_pushdown=off' 

large-pages 
binlog-row-event-max-size = 8192 
character_set_server = utf8 
collation_server = utf8_bin 
expire_logs_days = 1 
join_buffer_size = 262144 
max_allowed_packet = 32M 
max_connect_errors = 10000 
max_heap_table_size = 134217728 
query_cache_type = 0 
query_cache_size = 0 
slow-query-log = ON 
table_open_cache = 2048 
thread_cache_size = 64 
tmp_table_size = 134217728 
wait_timeout = 86400

# SHOW